TZ (CAS 2023788‑19‑2)
Dual GIP/GLP‑1 receptor agonist for metabolic pathway research (in vitro/preclinical)
CAS 2023788‑19‑2 is a 39‑amino acid synthetic peptide that acts as a dual agonist of GIP and GLP‑1 receptors, making it valuable for metabolic signaling, insulin‑secretion, and appetite‑regulation pathway research in controlled laboratory environments. Supplied lyophilized for stability; store at –20 °C. For research use only—not for human or veterinary applications.
Key Features & Research Applications
- Dual receptor engagement (GIP + GLP‑1): Enables synergistic investigation of incretin pathways for glucose homeostasis and appetite signaling in vitro/preclinical models [1] [3] [5].
- Engineered stability: Incorporates Aib substitutions and a C20 fatty diacid conjugation via a γ‑Glu‑(AEEA)₂‑Lys linker—design elements associated with extended half‑life and albumin binding in research contexts [1] [3].
- Lab‑friendly format: Supplied lyophilized; typical storage guidance –20 °C, protected from light/moisture; solubility references include DMSO for stock solutions under appropriate lab protocols [1] [4].
- Metabolic research models: Suitable for receptor‑binding studies, pathway mapping, comparative analyses versus single‑agonist compounds, and insulin signaling exploration in cell/animal models under institutional approvals.
Technical Specifications
| Attribute | Details |
|---|---|
| CAS Number | 2023788‑19‑2 [1] [2] |
| Molecular Formula | C₂₂₅H₃₄₈N₄₈O₆₈ [1] [2] |
| Molecular Weight | ~4,813 Da [1] [2] |
| Sequence (overview) | 39‑aa peptide; includes Aib substitutions and C20 diacid conjugation via γ‑Glu‑(AEEA)₂‑Lys (design features for stability) [1] [3] |
| Form | Lyophilized powder (research grade) [4] |
| Storage | –20 °C; dry, protected from light/moisture [1] [4] |
| Solubility (refs) | Soluble in DMSO; lab protocols may use aqueous buffers for working solutions [1] |
| Intended Use | Research use only—not for human/veterinary use, diagnostic, or therapeutic applications [4] |
FAQ
- Is this product intended for human use?
No. It is for research use only—not for human or veterinary applications, diagnosis, or therapy. - How should it be stored?
Store lyophilized vials at –20 °C, protected from light and moisture, and follow your lab’s SOPs and the product COA [1] [4].
For laboratory research use only. Not for human or veterinary use. Not for diagnostic, therapeutic, or clinical purposes.
GCA-TIR-30-1225-OR
Orange Cap
Total Batch QTY: 100
